News & Updates |
RESULTS
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Encouraging
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Unpredictable
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Sporadic miraculous results
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Unfortunately, it's impossible beforehand to
give any prognosis and forecasts about the treatment outcomes with
precise accuracy as in every case the patient's dynamics is very
individual and depends on number of factors.
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Any references/testimonials further we request
you to understand the science and don’t be carried by
testimonials as these
can be generated fake
AUTISM
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80% (8 of 10) experienced improvements
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Direct correlation between positive outcome and age, number of stem
cells administered and frequency.
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Results were significantly better in kids less than 8 year age
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Improved cognition and sensory processing
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Improved attention span
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Improved motor skills and coordination
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More confident
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Reduced hyperactivity
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Improved ability to socialize with others
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Meaningless play has reduced
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Hand and finger motor skill improvement
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Improved handwriting
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Improved speech
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Eating more independently
CEREBRAL PALSY
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Overall,60% improved
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Decrease in arm and hand spasticity 70%
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Improvements in hand and finger motor skills, coordination 60%
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Cognitive improvements materialized after about 3 months and
physical improvements started after 6 months.
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Leg and foot coordination improved in 50%
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Reduced lower limb spasticity 50%
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Able to walk 40 %
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Speech improved in almost 60% of patients.
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Improved cognition 20 %
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Attention span and ability to engage others 20%
SPINAL CORD INJURY
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Nearly 65-70%% of the treated patients experienced improvements.
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Patients saw average improvements of about 15% in ASIA motor score,
and approximately 20% in ASIA pin prick and light touch
measurements over a period of one year.
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Up to 65% of ASIA A patients could recover certain motor functions,
increased muscle strength, better stamina during physical
exercises, pelvic organs functions and improved bladder control as
well as the sensitivity.
VOLUNTARY TRUNK MUSCLE CONTROL
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Sitting without back support and able to stand
with support is experienced by 85% of Patients with upper thoracic
injury within 4 months.
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Better
coordination and walking ability with sensory improvement
though motor scores did not improve much was observed
in 90% of
patients
USEFUL MOTOR AND SENSORY RECOVERY
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Getting back sensation (feeling warm or cold
sensations/ touch) was reported in 67%
overall enhanced strength 65%
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Improved muscle function and
strength, including some ambulation
seen in 60% Patients till about 2 years.
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Bowel-and-bladder
function
improved in
55 % of patients
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Sexual function-
getting back erections was
reported by more than 30% of the patients
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Spasticity reduction
Spasms induced by attempted
movements diminishes significantly in 80% of patients
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Electrophysiological
measurements suggested improved nerve
conduction through the injury site in 62% of patients
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MRI (magnetic resonance imaging)
evaluations indicated
increased spinal-cord diameter in 40%
For
more information kindly visit:
go to pages on spinal
cord injury
PARKINSONS
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Total reversal of symptoms in the one patient.
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60 % of patients showed up to 50 %improvement in motor function
STROKE
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Overall 75% patients experienced improvements.
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MRI showed
25 % improvement in thickness of cortex in 60 % of patients
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Better arm use and coordination and improved motor skills in their
hands and fingers in 60 %
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Improved leg use and coordination as well as an increased ability
to stand and walk unassisted in 70 % of patients
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Speech improved in more than 65% of patients
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Vision improved in 40 %
MUSCULAR DYSTROPHY
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Pre-transplantation strength of 1- 2-/5 in the neck, shoulder,
upper, and lower extremities began to improve after each of the two
stem cell administrations, and reached a final 3-4/5 level by 6
months.
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Upper
extremity improvement in strength evolved from the incapacity to
lift up to 1 kg
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Trunk
balance and strength were also markedly improved.
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The patient
gained 3-5 kgs, along with an increased general activity level.
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The
frequency of respiratory infections decreased significantly by 50
-70 %
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The
inspiratory effort improved from -26-30- to - -38-42 cm H20.
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Increase in the number of donor-derived dystrophin being expressed
in the myofibers, (25to35 %).
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The improvement in muscular strength, clinical respiratory
function, and general level of activity are well maintained.
OPTIC ATROPHY
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Results vary between 40 -60 % depending on cause, duration of the
disease, age of the patient.
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In sub acute phase success rate exceeds up to 75 %.
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Improvement in the
visual acuity in (58 %) of eyes. It was marked, good and moderate
in 20%, 22 %and 16% eyes, respectively.
Slight improvement was seen in 2 % of cases.
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No eye showed
further deterioration of vision
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(52%) showed
improved vascularity of the disc, increased calibre of the retinal
arterioles and general improvement in the color of the peripheral
fundus
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47% was increase in
the field of vision, both central and peripheral.
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20% of them had no residual generalized peripheral
field constriction
MACULAR DEGENERATION
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Visual acuity
improved from hand motions to finger counting in 50 %
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Improved from 0 to
6 letters on the ETDRS visual acuity chart in 20 % of patients
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Vision also
improved in the patient with dry age-related macular degeneration.
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Neither patient lost vision
CORNEAL SCARRING
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90% eyes achieved epithelialization, corneal epithelial surface
remained stable, and intact after a mean follow up period of 2 yrs
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Visual acuity improved 0 to 4 letters on the ETDRS visual acuity chart
in 40 % of eyes.
OSTEOARTHRITIS OF KNEE
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WOMAC values (subsets and total) showed significant improvement
from baseline over the course of six months treatment (p < 0.001).
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The pain free distance covered during a Six minute walk (6MWD) also
significantly improved by 140 feet ((p<.001).
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Requirement of rescue medication decreased to once a week in 45%.
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The mean (SD) change for the percentage of painful days was 45.0
(38.7).
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25% patients demonstrated improved cartilage thickness by at least
0.01 mm as against 15% who lost thickness at least by 0.01 mm.
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55% patients showed improved Cell counts (below 500
microlitres) in Synovial fluid.
DELAYED AND NONUNION
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Accelerates healing
90 % patients showed quick
healing when used as a supplement with first surgery where high
chance of avascular necrosis and Nonunion exist e.g.-# neck femur/
talus/distal tibia
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Achieved union
in 95% of cases in cases of Delayed union (when X-ray showed no
callus in bridging construct or callus in stable construct in 3 -6
months)
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Healing seen
within 3 months in 80 % cases of atrophic non-union, failed
implants of long bones after autologous bone marrow concentrate.
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Cell therapy accelerated bone healing in the femur compared to in
the tibia.
AVASCULAR NECROSIS OF HEAD FEMUR
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Significant reduction in pain in all the patients
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Back to work within 6 months after treatment.
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Avoided the
progression of the disease effectively in 90 % of hips with Stage I
& II and in 40 % of hips with Stage III & IV disease.
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10 % of hips with stage 1 and II progressed to
Stage III: as compared to 50 % of Control patients progressing to
Stage III.
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6 % of Stage 1 and II of the hips
needed Total Hip replacement
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60 % Stage III & IV hips
needed Total Hip replacement
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Mean volume of
necrotic lesion in Control group increased while volume was reduced
in BM-MNC Group at 24 months
Critical Limb Ischemia
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Ankle-brachial index was significantly improved at rest
from 0.66 to 0.80, after stress from 0.64 to 0.76
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90 % of patients reported amelioration of rest pain and
pain free walking time by 24-week
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Pain-free walking distance increased from average of 150 m
to 550m
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Angiography evidence of collateral vessel formation
observed in 70 % of the patients
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Only 5 % patients needed amputation.
DIABETES
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Overall 80 % patients show significant
response over 2 years
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Fasting blood sugar from 8.5 to 9.5
mmol/L maintained to near diabetic goal of 7 in 80 %
of patients.
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HbA1c decline significantly by one year in 80
% of patients. (Average baseline values of from
8- 9.2 to 7.0 -7.5)
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30% achieved HbA1c values of <7%.
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Fasting C- peptide level improve significantly in 70 %
(0.6 -14 to 1.1to
2.2)
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50% of patients needed 50 percent less
requirement of insulin
within 6 months.
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20 % patients achieve reduction in insulin requirement by
75% as compared to baseline
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10 % patients are able to discontinue insulin completely
for 2years
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Insulin level basal mu/ml improved from mean of 16 to
13.5, and after meal from mean of 20 to 32.
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Triglycerides levels slowly reduce over time
but at times fluctuate as well
LIVER CIRRHOSIS (End Stage Liver
Disease)
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The doses of diuretics were reduced to half in 70 %.
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60 % had good reduction in Ascites
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Appetite improved significantly in 60 %
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Liver function tests (abnormal serum albumin and/or
bilirubin and/or prothrombin time/enzymes)
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Model for end-stage liver disease” (MELD) score improved
significantly in 30 % of patients and were maintained till 2 years.
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The improvement was most significant by 4- 6 months post
transplantation though changes could be observed as early as one
week in some patients.
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The MELD score and liver function tests in 25 % remained
stable (did not worsen) till 2 yrs
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CT showed that liver volumes in 30 % increased by six
months post transplantation.
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SF-36 questionnaire showed that the quality of life of all
patients had significantly till 2yrs of follow up.