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News & Updates
Stem cells help sex workers in Rehabilitation:
50 sex workers got a new life after being treated for VIRGINITY RESTORATION (VAGINOPLASTY/TIGHTNESS OF VAGINA) by Non-invasive procedure with their own adipose tissue derived cells- a joint effort by mother cell and NGO’s since the publication of last report...Know More

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Patient with Severe Brain Damage due to Thrombosis shows remarkable improvement:
Disabled 31 years old female because of Cerebral Venous Sinus Thrombosis for three years shows great signs of improvement. She was blinded, could not smell and had severe persisting headaches and could not walk properly due to incordination in my leg...Know More

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Ballad with Stem cells:
A portugese man nearly blind improves significantly after treatment with his own stem cells. the patient needed couple of boosters injections after initial treatment ...Know More

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The first successful noninvasive stem cell therapy for traumatic brain injury
A Man , suffering from altered sensorium, with complete visual loss, severe cognitive dysfunction and lack of movement in limbs For the past one and half year year regained full consciousness, reasonable memory, communication abilities and purposive movements in limbs ...Know More (a)
Know More (b)

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Upcoming training course in Stem Cell Research in Delhi & Chennai:
Mother Cell is holding a 2-day weekend Training Course in Delhi & Chennai.The training will cover Autologous, Bonemarrow & Adipose Stem Cell Technology: Extraction, isolation, Activation & Administration...Read More

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Stem-cells help American see again:
New Delhi, DNA: Seven years after he lost his sight following acute illness, it was no less than a miracle for 62-year-old Carl Stevens when he was able to catch a glimpse of the Taj Mahal after treatment...Read More

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Spinal cord injury is not incurable:
Translated version from Scandinavian news (Iceland) The omental transposition with good stabilization in contusion injuries has yielded very good results in all experimental treatments done so far: Dr Himanshu Bansal....Read More

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Tomorrow's Technology Today: Express Health Care:
Results with adipose tissue derived stem cell were encouraging in spinal cord injury. Bone marrow has a different cocktail of stem cells, and abundant quantity of growth factors which are necessary for cell proliferation and differentiation....Read More

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Stem cells can change your life: India Today
Thirty year old patient with complete spinal injury got restoration of bladder control soon six months after stem cell treatment. He feels a new life and has fathered a child now....Read More

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High on stem cell cocktail –boy fights cerebral palsy, New Indian Express:
A 5 yr old boy tried his own mother(stem cells) and is back on feet so much so that he is attending normal school....Read More

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Stem cells help youth get eyesight Deccan chronicle:
Stem cell therapy shows light of day to US medico; Times of India:
Doctors in the US had said that this 22 yr old had no chance of regain vision. When I reach US tomorrow, I will first go to my ophthalmologist and tell her than in can see you....Read More

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Stem cell cure for Incurable Blindness, Hindustan Times:
The Visual evoked potential tests showed that Mr Patil has got back ninety percent of his vision...Read More

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Omental transposition: institute of spinal cord injury Iceland:
Dr Himanshu Bansal (India) and colleagues have incorporated Goldsmith’s omental transposition ideas into their growing therapeutic armamentarium for SCI. In acute setting it is recommended only for pure contusion injuries....Read More

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International Data Base on Spinal cord Injury treatment modalities:
Stem cell technique of Dr bansal recognised by forums working for spinal injured: The concentrate maintains the fundamental nature of stem cells as well as has abundant growth factors. No physical or chemical harassment of these specialized cells is done....Read More

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Interview Dr bansal on possible treatment approaches on spinal cord injury:
Read More

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Ballad with Stem cells:
A portugese man nearly blind improves significantly after treatment with his own stem cells. the patient needed couple of boosters injections after initial treatment ...Know More

 

*Dr Bansal has designed a MRI based staging system to assess severity of injury.

 

Type 1-Pure contusion

(a) less then 50%

(b) more then 50% but not complete

(c) Complete

 

Type 2-Laceration

(a) less then 50%

(b) more then 50% but not complete transaction and

(c)complete transaction

 

Type 3- Maceration with obvious Gap

*Patients are also classified clinically with ASIA system.

#Borderline A/B patients will be screened  on the basis of MRI .

#only ASIA A will be taken up for treatment in acute phase .

#ASIA B and C will be treated only in chronic phase when all the possibility of natural recovery is exhausted.

 

According to the time window eligible patients will be further divided into three groups:

acute (< 2 weeks),

sub- acute (2-8 weeks) and

chronic > 8 weeks

 

In Acute Phase:

All Acute Patients of ASIA A, MRI type 1a and 1 b will undergo  spinal cord decompression and Stabilization, and Omentum transposition as early as possible .

All Acute ASIA A Patients other then MRI type 1a and 1 b will undergo spinal cord decompression and Stabilization only without omentum transposition.

No other active surgical treatment is needed in acute phase. Few of these patients show improvement. Those patients who still demonstrate persistent complete paralysis below the level of injury will be taken up for further treatment in subacute phase.

In subacute phase as the pathological entity to be tacked are

*slow down scar formation,

*provide growth facors which enhance neuronal sprouting.

*fasten wallerian degeneration as in Peripheral Nervous System

Amongst available promising approach is  intravenous/intraarterial/intrathecal/epidural/caudal injection of autologous stem cells without any manipulation before scar formation occurs.

Presence  of natural occurring growth factors boosts the regenerative process

Few of these patients show improvement. those patients who still demonstrate persistent complete paralysis below the level of injury are taken up for further treatment in chronic  phase.

 

In chronic phase therapy is directed towards:

*remyelination of intact axons

*addressing the Scar at the injury site.

 

Patient’s characteristics like age, duration of injury, psychological status and the possibility of aggressive rehabilitation influence the outcome.

Treatment depends on

presence of a rim of intact cord tissue extent & Type of scar

##Since scar has already formed by now unless we get rid of it regeneration can’t occur. Therapies tried in chronic phase without removing scar still help  by reactivation of intact but dormant/demyleinated axons.

myelomalacic changes in grey matter distal and proximal to cord.

**myelomalacic changes due to slow and prolonged wallerian degeneration in white matter are of less significance. What are more important are myelomalaciac changes in grey matter.

 

Available promising approaches:

 

Non invasive therapy (without surgical intervention) treatment consisting of conventional intravenous/intraarterial/intrathecal/epidural/caudal injection of autologous stem cells

## it is aimed for Reactivation of intact axons in chronic phase Indicated only  if some rim of intact tissue present around lesion.

Minimal invasive option of intraspinal/intralesional injection of autologous stem cells

*has recently yielded very good results probably both by virtue of reactivation & regeneration.

 Invasive procedure includes Duroplasty and scar reduction  implantaion  of stem cells /olfactory tissue with or without omentum transposition.

*Scar reduction with autologous olfactory tissue transplantations +/- omental transposition

*Scar reduction with intraspinal injections autologous stem cells transplantation +/- omental transposition

**With advanced neurosurgical techniques and skills Possibility of damage to intact neural  tissue during scar reduction is practically nil

** All procedures are from autologous tissue (i.e obtained  from patient ). The stem cells being used for the therapeutic protocol are autologous (patient's own) stem cell harvested either from the bone marrow,adipose tissue ,dental pulp or olfactory tissue.